N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

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The title compound, C15H24N2O4Si, was prepared by the reaction of (3-acetamido-5-nitrobenzyl)methanol with tert-butyldimethylsilyl chloride and is a key intermediate in the synthesis of novel nonsymmetrical DNA minor groove-binding gallagher fault finder battery agents.There are two independent molecules in the structure, which differ primarily in the rotation about the C—O bond next to the Si atom.Two strong N—H.O 5x4 tattoo hydrogen bonds align the molecules into a wide ribbon extending approximately parallel to the b axis.